I have had this same thing for nearly 1 1/2 - 2 years now.
It started on my finger near a slight cut (nothing to brag about really) when I was handeling some very acidic fruit at the facility that I manage (Cranberries). These small, fluid-filled bubbles have since spread very slowly but steadily across my hands and jumped ship down to my feet as well. When they moved to my feet, I knew it was a systemic issue when it moved to my feet.
I went to see a few dermatoligists and found a drug that seems to help... SORATAIN (Acitretin), 25mg tabs. It is a Vitamin A derivative and helps to thin the skin on the hands and feet. It works... dosen't get RID of the problem, but helps... If i'm having a flair up, I will increase the dose to 2 pills/day normal maintenance dose is 1-25mg tab/day. When I increase the dose, though, I see flakey skin on my face and my hands peel like a rattle snake!
Information on SORATAIN (Acitretin) is at the link below:https://www.psoriasis.org/NetCommunity/SSLPage.aspx?pid=444
This will tell you that you CANNOT get pregnant while on this pill for SEVERE birth defects are noted (up to 3 years after taking it!) Men shouldn't worry about this, even if wife is expecting to concieve.
So I've been using this and it helps. When I have some kind of infection (like a sinus infection) it seems to get worse... but I bump up the dose when I need to.
I'm not cured, but it helps where nothing seemed to help.
Small bubbles under the skin of the hands and feet... sometimes they can get to the size of a pencil eraser (inside the skin) but I deal with it and I know you shouldn't pop them, but popping them seems to stop them from growing very large.
Thanks for all of the comments... helps to know there are others out there.