the following is a couple productive hours research on keratosis pilaris;
**Melanin / Vitamin D-
melanin => vitamin D
people who generally have low amounts of melanin/vitamin d tend to have pail skin, diabetes and kp
(which are both hereditary, i have evidence of both in my family)
KP could possibly be a simple definciency of vitamin d/melatin.
(vitamin d is abundant in Fish Oils (supplemental pills) )
*Vitamin A-
Patients may turn to prescription vitamin A creams such as
Retin A / Tazorac/Avita / Differin to help restore a smooth texture
in recalcitrant cases or as a way to help treat KP complicated by acne.
People who have kp tend to have low amounts of vitamin a.
*Dermal Papilla-
Projection from the dermis that extends upward into the epidermis.
The Dermal Papilla helps anchor the epidermis and dermis.
Human Hair Follicle Dermal Papilla Cells (HFDPC)
are mesenchyme cells isolated from the hair papilla
of normal human scalp hair follicles. They are
cryopreserved at second passage, and can be cultured
and propagated 6 population doublings. HFDPC can be
used for the development and evaluation of hair growth
products. Hair papilla, in the adult hair follicle, plays
a crucial role in the dermal-epidermal interactions
that control hair production and events of the hair
growth cycle. It has been shown that cultured HFDPC can
stimulate hair growth when implanted into an amputated
follicle. When used in a reconstitution model, HFDPC is
an excellent tool for identifying cell populations within
the hair follicle and studying the effects of specific gene
products on hair follicle growth and development.
Pure Papilla is availiable for order..
Glycolic Acid (alpha hydroxy)-
An array of alpha hydroxy acids (AHAs) are
utilized in a dermatologist's quest to smooth
out keratosis pilaris. Glycolic acid works as
a chemical exfoliating agent.
M.D. Forte Hand & Body Cream is a buffered
20% glycolic acid cream potent enough to help
retexturize the skin.
Lactic Acid
Lactic acid is also an AHA. Dermatologists often
turn to OTC and Rx lactic acid products to palliate
(palliate has nothing to do with papilla) KP.
These can vary from low potency LactiCare Lotion
appropriate for young children, particularly if treating
areas on the face or far more potent AmLactin 12 % Moisturizing
Cream or AmLactin AP Moisturizing Cream for more stubborn,
itchy flare-ups. Prescription LacHydrin 12% is quite similar to
AmLactin.
Urea
Urea is one of those favorites of dermatology. It's role is to
soften the crustiest skin. Carmol comes in 2 OTC strengths:
Carmol 10 and Carmol 20. Both are excellent in the fight against KP.
For intractable KP, prescription Carmol 30 or Carmol 40 are medications
to consider. (exfoliant or moisturizer?)
Green Tea-
Green tea contains ECCG to fight the inflammation that causes the formation
of post inflammatory skin discoloration so commonly seen in KP.
(green tea bath?)
Therapeutic Dry Oil-
Sometimes an additional barrier that protects yet has the ability to
both smooth away the keratin and reduce inflammation helps promote more
rapid improvement. DERMAdoctor Handy Manum Anti-Itch Fissure Relief Serum
works to eliminate bumps by blending lactic, salicylic, malic and citric
acid with propylene glycol. Hydrocortisone is a proven medication rapidly
reducing inflammation and is bolstered by green tea and oat beta glucan.
DERMAdoctor Handy Manum Anti-Itch Fissure Relief Serum leaves a protective
barrier without leaving an unpleasant oily residue. A tiny dab goes a very
long way. Try applying at bedtime to enhance your regimen.
Immunomodulators-
Since KP is often thought of as a manifestation of eczema, it stands to
reason that new prescription medications such as Protopic and Elidel may
play a role in treating keratosis pilaris. I tend to reserve this for more
complex cases or for the patient who already has a tube at home, occasional
use may be a helpful, off label option.
Microdermabrasion-
KP is a chronic condition. Committing one self to never ending weekly sessions
of medical microdermabrasion rapidly add up financially. While effective at buffing
skin to a healthy glow, reserve this for special occasions and try less costly home
microdermabrasion options such as DermaNew Microdermabrasion Total Body Experience,
Neova Microdermabrasion Scrub or even an exfoliating scrub like
Peter Thomas Roth AHA/BHA Face & Body Polish.
(Urea + Glycolic Acid = safe, effective)
my recommended experimental treatment is:
vitamin a, vitamin d supplements
urea and glycolic acid combination cream
green tea (dunno how to use it though..)
also the therepeutic dry oil sounds quite effective, but has to be purchased from the link below.
i have yet to look into immunomodulators and microdermarasion, alothough immunomodulators seem more
suitable for a specific sub condition, while microdermabrasion sounds expensive and effective.
products
http://www.dermadoctor.com/pages/conditiondetail74.asp?X=1&WID=%7B8358334D%2D29DA%2D11D8%2D9196%2D0002B330452B%7Dmore..
Tazarotene-
Although keratosis pilaris is mainly a cosmetic nuisance,
it is often emotionally disturbing and difficult to treat.
Urea, lactic acid, topical corticosteroids, topical and
systemic retinoids, and other treatments have been used
with varying success. Tazarotene selectively transactivates
the retinoic acid receptors of the skin. It has a strong
antiproliferative effect and modulates keratinocyte
differentiation. Therefore, tazarotene has been tried in
the treatment of several keratinization disorders such as
Darier's disease and congenital ichthyoses.
"I tried tazarotene in an open study in the treatment of keratosis pilaris. After they had given informed consent, 20 consecutive patients with keratosis pilaris associated with atopy were instructed to apply an oil-in-water emulsion containing 0.01% tazarotene every evening for the next 4 to 8 weeks. In as soon as 2 weeks, keratosis pilaris gradually faded and resolved after 4 to 8 weeks. Because tazarotene has a low percutaneous absorption and is rapidly metabolized and eliminated,4 it may be beneficial for those with keratosis pilaris. Further, it may also hold promise for the treatment of other disturbing keratinization disorders."
Rosacea; i searched for about 2 minutes until i came accross this site
http://www.drnase.com/ . if that doesn't answer all your questions about how to reverse and irradicate rosacea, you don't have rosacea. (get the book)
i hope you all appreciate this, and please correct anything that seems incorrect, although im confident inmy research. i have a couple theories on KP, the vitamin d one is in here, although im sure if such a simple cure exsisted it would have been discovered and used long before some stupid kid thought of it. my other theory is based more on my thoughts rather then research, and will be my last resort if none of this works. i will post it if you can prove that these do not work. i'd appreciate it if someone could post some information on Tazarotene for me.
(PS some of this info was taken directly from sites, if it looks familiar)
