Author Topic: Again from NPF - Very interesting.  (Read 2787 times)

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Offline CalamityJane

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Again from NPF - Very interesting.
« on: Tuesday March 22, 2011, 08:38:35 PM »
Featured story
On the Horizon: Personalized Medicine
Advances in genetics may help pinpoint the best treatments

Thanks to the sequencing of the human genome , researchers have been able to identify dozens of genes that may play a role in psoriasis and psoriatic arthritis. Scores of yet-to-be-identified genes may also be involved. Read more about genetic hotspots for psoriasis.

Scientists think that different genes are to blame for psoriasis in different individuals.

Dr. Kristina Callis Duffin, assistant professor in the department of dermatology at the University of Utah, is working to link genetic variations to specific ways that psoriatic disease actually shows up on the skin or in the joints.

She says understanding this will eventually help pinpoint which treatment will work best for each person.

"I think of it as using the things that we know about the patient, like disease features, genetic markers and biomarkers, to determine what is the best therapy-meaning the most effective or the least toxic," she explained.

Identifying the genetic pathways that lead to psoriasis may also help drug developers make more targeted medicines.

Personalized medicine for psoriasis isn't around the corner, but it is on the horizon. Genetic tests are now helping identify effective treatments in several types of cancer and other diseases. Learn more.

"Researchers are at the beginning of linking genetic associations and the immunology of psoriasis," Callis Duffin said. "That's going to provide insight into why people get psoriasis, and help us figure out if there is a difference in treatment [effectiveness] for people who have specific gene variations."

Tips for finding the right doctor

fingerprint Psoriasis and psoriatic arthritis are chronic diseases. To stay healthy and live well, it's important to find a knowledgeable dermatologist and/or rheumatologist you can trust. Some things to think about:

    * Take the time to interview as many doctors as necessary to find a good fit.
    * Make sure your dermatologist has experience treating psoriasis. If you see a rheumatologist, make sure he or she has treated other people with psoriatic arthritis.
    * Make sure your doctor is familiar with the commonly accepted treatment options for psoriasis and/or psoriatic arthritis.
    * A good doctor will talk to you not only about your skin, but how the disease affects you emotionally. He or she will also monitor you for signs of related diseases like diabetes and heart disease.

Don't settle for a doctor who's not meeting your needs-you have a right to the best care for you.

The National Psoriasis Foundation Physician Directory can help you find a dermatologist or rheumatologist near you.

The American Academy of Dermatology also has a directory of member physicians.

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