I certainly was not attempting to insult, nor to provoke anything
Never the less Anthro, the reference to myself was all too obvious. This thread is no longer what I had intended it to be, (which was solely to list the explanations of the terminology, which could be used as a reference on this forum, such as the autoimmune articles thread is.) I am sure it is perfectly obvious to everyone that we would prefer it if the practioners in medicine would speak in modern terms, but they do not, and I personally do not think it will ever happen. This thread, instead of being a list explaining medical terminology, has now sidetracked into a discussion on the rights and wrongs of medical terminology, and now Langerhan cells. No personal perspective or additional thought was required or needed for this thread, it was
a list for information only, to use as a reference, and anyone could add to it with more terminologies, or definitions, in like manner, such as blue-sky kindly did.
I have seen the changes occurring for the past forty years.
Medical Terminology
always has been explained to the patient in "layman's terms".
No medical practioner would change this form of terminology in the medical field, when consulting with colleagues, writing articles, addressing seminars, corresponding on referals, or lecturing. I doubt therefore if you have seen changes regarding this over the last 40 years. We are I believe of a similar age? I have worked in the medical proffession and my friends and family still do, they haven't noticed any change in terminology over the past 40 years.
Quite frankly, as far as i am concerned I intend not to say more on this "debate". I was dealing with the here and now, it was not open for debate or argument but simply for reference as I explained earlier, I therefore ask you to respect that. If you insist on having a debate about the rights and wrongs of
using medical terminology, then please start your own thread, as I suggested in a previous post.
My (bunnie's note).....In the skin, Langerhan cells are immature dendritic cells.
And when the name Islets of Langerhans was originally coined, it only applied to the insulin producing cells of the pancreas.
That is
not so regarding naming cells Langerhan cells. The
Islets of Langerhan
alone refer to the pancreas. The other named
Langerhans cells of the skin were discovered
first, in
1868, in fact a year
before the Islets of Langerhans in the pancreas, which he discovered in
1869!If there is some good reason that the dendritic immunity modulating cells should also bear the name Langerhans, I would be interested to hear it. From my perspective, only additional ambiguity and a potential for confusion has been achieved.
here is your answer to both quotes above... It is in fact the other way round. Langerhan discovered
the cells in the skin first, (the immature dendritic cell, Antigen presenting cell) , these are not
"islet cells" (which secrete a hormone-insulin in the pancreas,)
these were discovered a year
later! Langerhans cells - Skin cells concerned with the immune response and which sometimes contain Langerhans granules. In 1868, Langerhans used the technique taught to him by Julius Friedrich Cohnheim to stain a sample of human skin with gold chloride and identified the cells which now bear his name. From their appearance, Langerhans believed they were nerve cells. However they are a form of dendritic cells.
Islets of Langerhans - Pancreatic cells which produce insulin. Langerhans discovered these cells during his studies for his doctorate at the Berlin Pathological Institute in 1869.
see also...
http://en.wikipedia.org/wiki/Islets_of_LangerhansDefinitions of LANGERHANS CELLS on the Web:Dendritic cells in the skin that pick up an antigen and transport it to the lymph nodes. See also Antigen; Dendritic Cells; Lymph Nodes.
www.aidsinfobbs.org/letters/l.htmlLangerhans cells are dendritic cells that present antigens to the immune system. They are found in the prickle cell layer of the epidermis. Epidermis
dermnetnz.org/glossary.html
Dendritic, antigen-presenting cells that contains characteristic racket-shaped granules, known as birbeck granules, and which expressing the CD1a antigen. Principally found in the stratified squamous epithelium.
www.nature.com/nrmicro/journal/v1/n1/glossary/nrmicro729_glossary.htmlEpidermal dendritic cell that functions as an antigen-presenting cell (APC) during an immune response.
www.nutrabio.com/Definitions/definitions_l.htm http://dermnetnz.org/dermal-infiltrative/langerhans.htmlLangerhans cells are immune cells that are normally found within the epidermis where they act as antigen-presenting cells in an early warning system fighting foreign material such as bacteria. They may migrate to the local lymph glands but usually return to the skin.
http://www.mattek.com/pages/products/dendritic_cellsDendritic cells (DC) play a key role in the immunological reactions throughout the body. Dendritic cells (DC) and their immature counterparts, Langerhans cells (LC), are highly specialized antigen-presenting cells (APC) located in the skin, mucosa, and lymphoid tissues. DC and LC play a key role in the induction phase of contact allergenicity, and it is likely that these cells can be used to develop in vitro assays for contact sensitization and other immunological reactions of the body.
http://en.wikipedia.org/wiki/Islets_of_LangerhansIt is these cells which are part of the malfunction in autoimmune disease, they are in over production and fail to regulate the inflammation in the abnormal (autoimmune response).
There are posts on the liga thread concerning this too.
Bunnie